Modelling pathology progression in Parkinson’s disease phenotypes
Modeling pathological progression pathways in Parkinson's disease reveals two main patient phenotypes: body first and brain first. Clinical differences include variations in motor and cognitive decline, impacting treatment strategies. Data from the Parkinson Progression Marker Initiative shows that body first patients face worse outcomes and faster progression. The study also explores biological mechanisms, particularly the influence of gut microbiota on disease severity.Speaker: Massimiliano Passaretti
Level: Expert
Topics in this course:
