• Episode 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

    EANcast explores groundbreaking research on somatic expansion in Huntington's disease (HD). Featuring Jean-Marc Burgunder and Sandrine Humbert, this episode delves into two pivotal papers examining CHG repeat increases in brain tissue. Discover how advanced single-cell technologies reveal the role of mismatch repair genes in HD pathology and potential therapeutic avenues.

    Topics in this course:

    Huntingtons Disease Neurology Somatic Expansion Ea Ncast Neuroscience